MolNFT v1 · #254431 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q5F5J4)

Q5F5J4: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q5F5J4)”. 8 pockets (best druggability 0.68). MolNFT v1 #254431 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q5F5J4
Type: protein
Length: 864 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x9377360E5534e0b32ED177Ed6f54ffBbf020C961
Molecule: DNA mismatch repair protein muts
UniProt: Q5F5J4
Pockets: 8 · best druggability 0.68

Structure

1 distinct chain · 45% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein muts	protein	864	45% helix, 19% strand	Q5F5J4

Pockets

8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	729	0.68	0.76	74	empty
2	483	0.65	0.77	35	empty
3	102	0.64	0.90	24	empty
4	372	0.63	0.78	36	empty
5	150	0.46	0.76	20	empty

Compared structures

5X9W · Mismatch repair protein · an experimental structure of the same protein · chain A against A, TM-score 0.88
5YK4 · Mismatch repair protein · an experimental structure of the same protein · chain A against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5F5J4
Elsewhere: UniProt Q5F5J4 · AlphaFold DB Q5F5J4

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