UniProt Q5F5J4
DNA mismatch repair protein MutS (Q5F5J4)
DNA mismatch repair protein MutS (UniProt Q5F5J4): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 48 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5F5J4
- Protein
- DNA mismatch repair protein MutS
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 48 · 3 records with a druggable one
Structures
5 records of Q5F5J4 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5X9W | Mismatch Repair Protein | x-ray diffraction | A, B | ANP | 20 (best 0.69) |
| 5X9W | Mismatch repair protein | x-ray diffraction | A, B | ANP | — |
| 5YK4 | Mismatch Repair Protein | x-ray diffraction | A, B | ADP | 20 (best 0.72) |
| 5YK4 | Mismatch repair protein | x-ray diffraction | A, B | ADP | — |
| Q5F5J4 | AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q5F5J4) | predicted | A | — | 8 (best 0.68) |
Ligands
Experiment against prediction
- 5X9W chain B against the predicted model Q5F5J4: TM-score 0.98, RMSD 1.39 Å
- 5X9W chain A against the predicted model Q5F5J4: TM-score 0.98, RMSD 1.41 Å
- 5X9W chain A against the predicted model Q5F5J4: TM-score 0.98, RMSD 1.41 Å
- 5YK4 chain A against the predicted model Q5F5J4: TM-score 0.98, RMSD 1.49 Å
- 5YK4 chain A against the predicted model Q5F5J4: TM-score 0.98, RMSD 1.49 Å
- 5YK4 chain B against the predicted model Q5F5J4: TM-score 0.97, RMSD 1.70 Å
- 5YK4 chain B against the predicted model Q5F5J4: TM-score 0.97, RMSD 1.70 Å
Elsewhere
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