Research workbench
Complex structure of TSE3-TSI3
Analyse Complex structure of TSE3-TSI3 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4M5F
- Type
- protein
- Length
- 523 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein
- UniProt
- Q9HYC5, Q9HYC4
- Ligands
- CA, PO4
- Pockets
- 5 · best druggability 0.69
Structure
x-ray diffraction · 2 distinct chains · 48% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein | protein | 399 | 61% helix, 2% strand | Q9HYC5 |
| B | Uncharacterized protein | protein | 124 | 6% helix, 58% strand | Q9HYC4 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 564 | 0.69 | 0.78 | 54 | PO4 |
| 2 | 130 | 0.46 | 0.78 | 27 | empty |
| 3 | 51 | 0.36 | 0.80 | 12 | empty |
| 4 | 65 | 0.34 | 0.76 | 16 | empty |
| 5 | 85 | 0.33 | 0.74 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 988 Ų buried · 24 hydrogen bonds · protein-protein
Compared structures
- 4M5F · complex structure of Tse3-Tsi3 · the same entry in another collection · chain A against A, TM-score 1.00
- Q9HYC4 · AlphaFold monomer V2.0 prediction for immune protein TSI3 (Q9HYC4) · a predicted model of the same protein · chain B against A, TM-score 0.99
- Q9HYC5 · AlphaFold monomer V2.0 prediction for peptidoglycan muramidase TSE3 (Q9HYC5) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HYC5
- Every structure of UniProt Q9HYC4
- Elsewhere: RCSB PDB 4M5F · PDBe 4M5F · UniProt Q9HYC5 · UniProt Q9HYC4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.