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UniProt Q9HYC4

Stimulator of interferon genes protein,Immune protein Tsi3 (Q9HYC4)

Stimulator of interferon genes protein,Immune protein Tsi3 (UniProt Q9HYC4): 14 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 58 pockets. Binding sites, druggability and experiment against…

UniProt
Q9HYC4
Protein
Stimulator of interferon genes protein,Immune protein Tsi3
Experimental structures
14
Predicted models
1
Ligands
5
Pockets
58 · 8 records with a druggable one

Structures

15 records of Q9HYC4 in the MolNFT archive: 14 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
3WA5Crystal Structure of type VI peptidoglycan muramidase effector Tse3 in complex with its cognate…x-ray diffractionBCA2 (best 0.72)
3WA5Crystal structure of type VI peptidoglycan muramidase effector TSE3 in complex with its cognate…x-ray diffractionB——
4LUQCrystal structure of virulence effector Tse3 in complex with neutralizer Tsi3x-ray diffractionC, D—2 (best 0.69)
4LUQCrystal structure of virulence effector TSE3 in complex with neutralizer TSI3x-ray diffractionC, D——
4M5Fcomplex structure of Tse3-Tsi3x-ray diffractionBCA, PO43 (best 0.69)
4M5FComplex structure of TSE3-TSI3x-ray diffractionB——
4N7SCrystal structure of Tse3-Tsi3 complex with Zinc ionx-ray diffractionB, DZN, CA, NA5 (best 0.77)
4N7SCrystal structure of TSE3-TSI3 complex with zinc ionx-ray diffractionB, D——
4N80Crystal structure of Tse3-Tsi3 complexx-ray diffractionBZN, CA2 (best 0.68)
4N80Crystal structure of TSE3-TSI3 complexx-ray diffractionB——
4N88Crystal structure of Tse3-Tsi3 complex with calcium ionx-ray diffractionB, DCA4 (best 0.71)
4N88Crystal structure of TSE3-TSI3 complex with calcium ionx-ray diffractionB, D——
8IK0Cryo-EM structure of Stimulator of interferon geneselectron microscopyA, B, C, F, D, G, E, H—20 (best 0.83)
8IK3Structure of Stimulator of interferon genes/ligand complexelectron microscopyA, B, C, D, E, G, F, H1SY20 (best 0.85)
Q9HYC4AlphaFold monomer V2.0 prediction for immune protein TSI3 (Q9HYC4)predictedA——

Ligands

  • CA · Calcium ion · in 5 records
  • ZN · Zinc ion · in 2 records
  • 1SY · cGAMP · in 1 record
  • NA · Sodium ion · in 1 record
  • PO4 · Phosphate ion · in 1 record

Experiment against prediction

Elsewhere

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