Structure of SHE3P amino terminus.

Structure

x-ray diffraction · 6 distinct chains · 96% helix, 0% strand (DSSP).

Ligands and binding sites

• DY · Dysprosium ion · metal · 26 copies · chains A, B, E, G, C, D, F, H
• PT · Platinum (II) ion · metal · 6 copies · chains A, F, B, E, C, G, D, H
• SO4 · Sulfate ion · ion · 29 copies · chains A, E, F, G, B, H, C, D
• EDO · 1,2-ethanediol · additive · 7 copies · chains B, D, E, F, H
• IPA · Isopropyl alcohol · additive · 6 copies · chains C, D, E, F
• DTT · 2,3-dihydroxy-1,4-dithiobutane · additive · chains A, B, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Interfaces

18 interfaces between chains.

• D–E · 1313 Ų buried · 19 hydrogen bonds · protein-protein
• B–H · 1301 Ų buried · 18 hydrogen bonds · protein-protein
• A–F · 1300 Ų buried · 17 hydrogen bonds · protein-protein
• B–E · 1281 Ų buried · 14 hydrogen bonds · protein-protein
• C–G · 1269 Ų buried · 16 hydrogen bonds · protein-protein

Compared structures

• 4LL7 · Structure of She3p amino terminus. · the same entry in another collection · chain H against H, TM-score 1.00
• P38272 · AlphaFold monomer V2.0 prediction for SWI5-dependent ho expression protein 3 (P38272) · a predicted model of the same protein · chain C against A, TM-score 0.92

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P38272
• Elsewhere: RCSB PDB 4LL7 · PDBe 4LL7 · UniProt P38272