Ligand · DTT
DTT · 2,3-dihydroxy-1,4-dithiobutane
DTT, 2,3-dihydroxy-1,4-dithiobutane (C4 H10 O2 S2, 154.2 g/mol), in the MolNFT structures on GenesisL1: bound in 159 records (124 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…
- Component
- DTT
- Formula
- C4 H10 O2 S2
- Class
- additive
- Structures
- 159
- PDB entries
- 124
Binding sites
DTT in 159 structures; the first of them:
- 4ZA1 · Crystal Structure of NosA Involved in Nosiheptide Biosynthesis · DTT A201 · binds LEU28, TYR31, LEU32, VAL37, TRP51, GLY80, VAL81, SER82 and 3 more
- 4ZD4 · Catalytic domain of Sst2 F403W mutant · DTT B507 · binds LYS294, HIS304, HIS332, ASN333, LEU334, GLN428
- 5F5L · The structure of monooxygenase KstA11 in the biosynthetic pathway of kosinostatin · DTT A306 · binds ALA120, GLU127, TRP130, THR131, ARG134
- 5FA9 · Bifunctional Methionine Sulfoxide Reductase AB (MsrAB) from Treponema denticola · DTT A402 · binds ALA158, LEU159, LYS160, GLN242, LYS262
- 5GXG · High-resolution crystal structure of the electron transfer complex of cytochrome p450cam… · DTT A506 · binds PHE87, THR101, GLY248, THR252, VAL295, ASP297, VAL396
- 5HGI · Crystal structure of apo human IRE1 alpha · DTT A1007 · binds GLU807, HIS825, TYR945, GLU949
- 5IRS · crystal structure of the proteasomal Rpn13 PRU-domain · DTT A201 · binds CYS88, PRO89, SER90
- 5LBO · Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-001 · DTT A1010 · binds THR134, ASP187
- 5N2G · Structure of the E9 DNA polymerase from vaccinia virus in complex with manganese · DTT A1110 · binds GLU339, TYR472, TYR473, LYS478, ASP654, TYR658
- 5ON9 · Crystal structure of NikA in complex with reduced Fe-L1… · DTT A603 · binds TRP10, PRO11, ARG205, GLY219, ASN220, GLY222, LEU223
- 5TXZ · DNA Polymerase Mu Reactant Complex, 100mM Mg2+ (15 min) · DTT A505 · binds CYS180
- 5TYB · DNA Polymerase Mu Reactant Complex, 10mM Mg2+ (7.5 min) · DTT A505 · binds GLU161, ALA164, CYS180
- 5TYC · DNA Polymerase Mu Reactant Complex, 10mM Mg2+ (15 min) · DTT A507 · binds CYS180
- 5TYD · DNA Polymerase Mu Reactant Complex, 10 mM Mg2+ (45 min) · DTT A504 · binds GLU161, ALA164, CYS180
- 5TYY · DNA Polymerase Mu Product Complex, Mn2+ (60 min) · DTT A508 · binds CYS180
- 5UL3 · Structure of Cobalamin-dependent S-adenosylmethionine radical enzyme OxsB with… · DTT A803 · binds ASP362, GLU363, ALA397
- 5Z7A · Crystal structure of NDP52 SKICH region · DTT A202 · binds GLN22, ARG117, GLY118, ALA119, HIS19, GLN22
- 5Z87 · Structural of a novel b-glucosidase EmGH1 at 2.3 angstrom from Erythrobacter marinus · DTT A801 · binds TYR93, GLU130, PHE178, ARG192, LYS233, HIS234, HIS281, ASP313 and 3 more
- 6DEB · Crystal Structure of Bifunctional Enzyme FolD-Methylenetetrahydrofolate… · DTT B306 · binds LEU178, ASN179, ALA180, GLY181, ALA165, ARG171, HIS188, ILE189 and 1 more
- 6DX5 · Crystal structure of the viral OTU domain protease from Farallon virus · DTT B301 · binds TYR78, TYR122, TRP123, ASP127
- 6E0A · Crystal Structure of Helicobacter pylori TlpA Chemoreceptor Ligand Binding Domain · DTT B305 · binds VAL33, SER69, HIS70, ASN166, GLU167
- 6EBC · OhrB (Organic Hydroperoxide Resistance protein) wild type from Chromobacterium violaceum… · DTT B201 · binds CYS60, GLY63, SER64, PRO125, PRO49, GLU50, ILE88, PHE95
- 6FIJ · Structure of the loading/condensing region (SAT-KS-MAT) of the cercosporin fungal… · DTT B1408 · binds VAL213, LEU313, ASP314, MET316, ALA317, LEU339, SER340, PHE341 and 4 more
- 6HR7 · HMG-CoA reductase from Methanothermococcus thermolithotrophicus apo form at 2.4 A… · DTT A503 · binds ASN90, PHE93, GLU360, LEU361, GLY363, LYS372, SER43
- 6JKE · Discovery and the crystal structure of NS5 in complex with the N-terminal bromodomain of… · DTT A203 · binds GLN94, TRP97, ARG100
- 6JV9 · Crystal Structure of Human CRMP2 1-532, unmodified · DTT B601 · binds SER288, HIS289, SER292, LYS293, LYS297
Residues it binds most
CYS 98, ARG 55, GLU 58, ALA 56, ASN 46, TRP 40, TYR 40, ASP 49, LEU 45, GLY 45 (residue and the binding sites it lines).
Found with
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.