Research workbench

Cyclic di-gmp sensing via the innate immune signaling protein sting

Analyse Cyclic di-gmp sensing via the innate immune signaling protein sting in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4F9E
Type: protein
Length: 173 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transmembrane protein 173
UniProt: Q86WV6
Pockets: 1 · best druggability 0.29

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transmembrane protein 173	protein	173	43% helix, 20% strand	Q86WV6

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	71	0.29	0.73	18	empty

Compared structures

4F9E · Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING · the same entry in another collection · chain A against A, TM-score 1.00
Q86WV6 · AlphaFold monomer V2.0 prediction for stimulator of interferon genes protein (Q86WV6) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q86WV6
Elsewhere: RCSB PDB 4F9E · PDBe 4F9E · UniProt Q86WV6

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