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Crystal structure of epithelial adhesin 1 a domain (EPA1A) from candida glabrata in complex with the T-antigen (GALB1-3GALNAC)

Analyse Crystal structure of epithelial adhesin 1 a domain (EPA1A) from candida… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4D3W
Type: protein
Length: 226 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Epithelial adhesin 1
UniProt: Q6FUW5
Ligands: NGA, GAL, CA
Pockets: 1 · best druggability 0.35

Structure

x-ray diffraction · 1 distinct chain · 8% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Epithelial adhesin 1	protein	226	8% helix, 40% strand	Q6FUW5

Ligands and binding sites

NGA · 2-acetamido-2-deoxy-beta-D-galactopyranose · sugar · chains A
GAL · beta-D-galactopyranose · sugar · chains A
CA · Calcium ion · metal · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	64	0.35	0.77	14	GOL

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

4D3W · Crystal Structure of Epithelial Adhesin 1 A domain (Epa1A) from Candida glabrata in… · the same entry in another collection · chain A against A, TM-score 1.00

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6FUW5
Elsewhere: RCSB PDB 4D3W · PDBe 4D3W · UniProt Q6FUW5

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