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Crystal structure of epithelial adhesin 6 a domain (EPA6A) from candida glabrata in complex with GALB1-4GLCNAC

Analyse Crystal structure of epithelial adhesin 6 a domain (EPA6A) from candida… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4COY
Type: protein
Length: 232 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Epithelial adhesin 6
UniProt: Q6FX55
Ligands: NAG, GAL, CA
Pockets: 2 · best druggability 0.39

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Epithelial adhesin 6	protein	232	6% helix, 38% strand	Q6FX55

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
GAL · beta-D-galactopyranose · sugar · chains A
CA · Calcium ion · metal · chains A
ACT · Acetate ion · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	95	0.39	0.76	22	empty
2	54	0.29	0.75	17	empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

4COY · Crystal Structure of Epithelial Adhesin 6 A domain (Epa6A) from Candida glabrata in… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6FX55
Elsewhere: RCSB PDB 4COY · PDBe 4COY · UniProt Q6FX55

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