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N-domain of HTRA1

Analyse N-domain of HTRA1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3TJQ
Type: protein
Length: 106 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Serine protease HTRA1
EC: 3.4.21.-
UniProt: Q92743
Ligands: PT, CL, SCN

Structure

x-ray diffraction · 1 distinct chain · 15% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Serine protease HTRA1 (EC 3.4.21.-)	protein	106	15% helix, 24% strand	Q92743

Ligands and binding sites

PT · Platinum (II) ion · metal · 2 copies · chains A
CL · Chloride ion · ion · 6 copies · chains A
SCN · Thiocyanate ion · ion · 4 copies · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 7 disulfide (disulfide).

Compared structures

3TJQ · N-domain of HtrA1 · the same entry in another collection · chain A against A, TM-score 1.00
Q92743 · AlphaFold monomer V2.0 prediction for serine protease HTRA1 (Q92743) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q92743
Elsewhere: RCSB PDB 3TJQ · PDBe 3TJQ · UniProt Q92743

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