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Crystal structure of URE3-binding protein, (D127A,N129A) mutant, iodide phased

Analyse Crystal structure of URE3-binding protein, (D127A,N129A) mutant, iodide phased in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3SIA
Type: protein
Length: 212 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: URE3-bp sequence specific DNA binding protein
UniProt: Q9GSV7
Ligands: CA, IOD, CL
Pockets: 4 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 64% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	URE3-bp sequence specific DNA binding protein	protein	212	64% helix, 3% strand	Q9GSV7

Ligands and binding sites

CA · Calcium ion · metal · 2 copies · chains A
IOD · Iodide ion · ion · 26 copies · chains A
CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	125	0.45	0.77	18	IOD
2	122	0.43	0.76	19	IOD
3	95	0.41	0.76	15	empty
4	53	0.27	0.74	13	IOD

Compared structures

3SIA · Crystal structure of URE3-binding protein, (D127A,N129A) mutant, iodide phased · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9GSV7
Elsewhere: RCSB PDB 3SIA · PDBe 3SIA · UniProt Q9GSV7

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