Research workbench

Engineering domain-swapped binding interfaces by mutually exclusive folding: insertion of ubiquitin into position 103 of barnase

Analyse Engineering domain-swapped binding interfaces by mutually exclusive folding… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3Q3F
Type: protein
Length: 188 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RIBONUCLEASE/UBIQUITIN chimeric protein
UniProt: P00648, P0CG48
Ligands: SO4
Pockets: 1 · best druggability 0.65

Structure

x-ray diffraction · 1 distinct chain · 22% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RIBONUCLEASE/UBIQUITIN chimeric protein	protein	188	22% helix, 24% strand	P00648, P0CG48

Ligands and binding sites

SO4 · Sulfate ion · ion · 16 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	261	0.65	0.82	38	SO4

Compared structures

3Q3F · Engineering Domain-Swapped Binding Interfaces by Mutually Exclusive Folding: Insertion of… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00648
Every structure of UniProt P0CG48
Elsewhere: RCSB PDB 3Q3F · PDBe 3Q3F · UniProt P00648 · UniProt P0CG48

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