UniProt P00648
Ribonuclease (P00648)
Ribonuclease (UniProt P00648), EC 3.1.27.-: 104 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P00648
- Protein
- Ribonuclease
- EC
- 3.1.27.-
- Experimental structures
- 104
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 10 · 2 records with a druggable one
Structures
105 records of P00648 in the MolNFT archive: 104 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1A2P | Barnase wildtype structure at 1.5 ångströms resolution | x-ray diffraction | A, B, C | — | — |
| 1A2P | Barnase wildtype structure at 1.5 ångströms resolution | x-ray diffraction | A, B, C | — | — |
| 1B20 | Deletion of a buried salt-bridge in barnase | x-ray diffraction | A, B, C | — | — |
| 1B20 | Deletion of a buried salt-bridge in barnase | x-ray diffraction | A, B, C | — | — |
| 1B21 | Deletion of a buried salt bridge in barnase | x-ray diffraction | A, B, C | — | — |
| 1B21 | Deletion of a buried salt bridge in barnase | x-ray diffraction | A, B, C | — | — |
| 1B27 | Structural response to mutation at a protein-protein interface | x-ray diffraction | A, B, C | — | — |
| 1B27 | Structural response to mutation at a protein-protein interface | x-ray diffraction | A, B, C | — | — |
| 1B2S | Structural response to mutation at a protein-protein interface | x-ray diffraction | A, B, C | — | — |
| 1B2S | Structural response to mutation at a protein-protein interface | x-ray diffraction | A, B, C | — | — |
| 1B2U | Structural response to mutation at a protein-protein interface | x-ray diffraction | A, B, C | — | — |
| 1B2U | Structural response to mutation at a protein-protein interface | x-ray diffraction | A, B, C | — | — |
| 1B2X | Barnase wildtype structure at pH 7.5 from a CRYO_COOLED crystal at 100K | x-ray diffraction | A, B, C | — | — |
| 1B2X | Barnase wildtype structure at pH 7.5 from a CRYO_COOLED crystal at 100K | x-ray diffraction | A, B, C | — | — |
| 1B2Z | Deletion of a buried salt bridge in barnase | x-ray diffraction | A, B, C | — | — |
| 1B2Z | Deletion of a buried salt bridge in barnase | x-ray diffraction | A, B, C | — | — |
| 1B3S | Structural response to mutation at a protein-protein interface | x-ray diffraction | A, B, C | — | — |
| 1B3S | Structural response to mutation at a protein-protein interface | x-ray diffraction | A, B, C | — | — |
| 1BAN | The contribution of buried hydrogen bonds to protein stability: the crystal structures of two… | x-ray diffraction | A, B, C | — | — |
| 1BAN | The contribution of buried hydrogen bonds to protein stability: the crystal structures of two… | x-ray diffraction | A, B, C | — | — |
| 1BAO | The contribution of buried hydrogen bonds to protein stability: the crystal structures of two… | x-ray diffraction | A, B, C | — | — |
| 1BAO | The contribution of buried hydrogen bonds to protein stability: the crystal structures of two… | x-ray diffraction | A, B, C | — | — |
| 1BGS | Recognition between a bacterial ribonuclease, barnase, and its natural inhibitor, barstar | x-ray diffraction | A, B, C | — | — |
| 1BGS | Recognition between a bacterial ribonuclease, barnase, and its natural inhibitor, barstar | x-ray diffraction | A, B, C | — | — |
| 1BNE | Barnase A43C/S80C disulfide mutant | x-ray diffraction | A, B, C | — | — |
| 1BNE | Barnase A43C/S80C disulfide mutant | x-ray diffraction | A, B, C | — | — |
| 1BNF | Barnase T70C/S92C disulfide mutant | x-ray diffraction | A, B, C | — | — |
| 1BNF | Barnase T70C/S92C disulfide mutant | x-ray diffraction | A, B, C | — | — |
| 1BNG | Barnase S85C/H102C disulfide mutant | x-ray diffraction | A, B, C | — | — |
| 1BNG | Barnase S85C/H102C disulfide mutant | x-ray diffraction | A, B, C | — | — |
| 1BNI | Barnase wildtype structure at pH 6.0 | x-ray diffraction | A, B, C | — | — |
| 1BNI | Barnase wildtype structure at pH 6.0 | x-ray diffraction | A, B, C | — | — |
| 1BNJ | Barnase wildtype structure at pH 9.0 | x-ray diffraction | A, B, C | — | — |
| 1BNJ | Barnase wildtype structure at pH 9.0 | x-ray diffraction | A, B, C | — | — |
| 1BNR | BARNASE | solution nmr | A | — | — |
| 1BNR | BARNASE | solution nmr | A | — | — |
| 1BNS | Structural studies of barnase mutants | x-ray diffraction | A, B, C | — | — |
| 1BNS | Structural studies of barnase mutants | x-ray diffraction | A, B, C | — | — |
| 1BRG | Crystallographic analysis of phe->leu substitution in the hydrophobic core of barnase | x-ray diffraction | A, B, C | — | — |
| 1BRG | Crystallographic analysis of phe->leu substitution in the hydrophobic core of barnase | x-ray diffraction | A, B, C | — | — |
| 1BRH | Barnase mutant with leu 14 replaced by ala | x-ray diffraction | A, B, C | — | — |
| 1BRH | Barnase mutant with leu 14 replaced by ala | x-ray diffraction | A, B, C | — | — |
| 1BRI | Barnase mutant with ile 76 replaced by ala | x-ray diffraction | A, B, C | — | — |
| 1BRI | Barnase mutant with ile 76 replaced by ala | x-ray diffraction | A, B, C | — | — |
| 1BRJ | Barnase mutant with ile 88 replaced by ala | x-ray diffraction | A, B, C | — | — |
| 1BRJ | Barnase mutant with ile 88 replaced by ala | x-ray diffraction | A, B, C | — | — |
| 1BRK | Barnase mutant with ile 96 replaced by ala | x-ray diffraction | A, B, C | — | — |
| 1BRK | Barnase mutant with ile 96 replaced by ala | x-ray diffraction | A, B, C | — | — |
| 1BRN | Subsite binding in an RNase: structure of a barnase-tetranucleotide complex at 1.76 ångströms… | x-ray diffraction | L, M | — | — |
| 1BRN | Subsite binding in an RNase: structure of a barnase-tetranucleotide complex at 1.76 ångströms… | x-ray diffraction | L, M | — | — |
| 1BRS | Protein-protein recognition: crystal structural analysis of a barnase-barstar complex at 2.0-a… | x-ray diffraction | A, B, C | — | — |
| 1BRS | Protein-protein recognition: crystal structural analysis of a barnase- barstar complex at 2.0-a… | x-ray diffraction | A, B, C | — | — |
| 1BSA | Crystal structural analysis of mutations in the hydrophobic cores of barnase | x-ray diffraction | A, B, C | — | — |
| 1BSA | Crystal structural analysis of mutations in the hydrophobic cores of barnase | x-ray diffraction | A, B, C | — | — |
| 1BSB | Crystal structural analysis of mutations in the hydrophobic cores of barnase | x-ray diffraction | A, B, C | — | — |
| 1BSB | Crystal structural analysis of mutations in the hydrophobic cores of barnase | x-ray diffraction | A, B, C | — | — |
| 1BSC | Crystal structural analysis of mutations in the hydrophobic cores of barnase | x-ray diffraction | A, B, C | — | — |
| 1BSC | Crystal structural analysis of mutations in the hydrophobic cores of barnase | x-ray diffraction | A, B, C | — | — |
| 1BSD | Crystal structural analysis of mutations in the hydrophobic cores of barnase | x-ray diffraction | A, B, C | — | — |
| 1BSD | Crystal structural analysis of mutations in the hydrophobic cores of barnase | x-ray diffraction | A, B, C | — | — |
45 records more on the page itself.
Ligands
- PO4 · Phosphate ion · in 2 records
Experiment against prediction
- 1X1W chain A against the predicted model P00648: TM-score 1.00, RMSD 0.24 Å
- 1BRS chain A against the predicted model P00648: TM-score 1.00, RMSD 0.26 Å
- 1X1Y chain A against the predicted model P00648: TM-score 0.99, RMSD 0.28 Å
- 6PQK chain C against the predicted model P00648: TM-score 0.99, RMSD 0.29 Å
- 1X1X chain C against the predicted model P00648: TM-score 0.99, RMSD 0.29 Å
- 2F5W chain A against the predicted model P00648: TM-score 0.99, RMSD 0.30 Å
- 2F5M chain A against the predicted model P00648: TM-score 0.99, RMSD 0.31 Å
- 1X1X chain A against the predicted model P00648: TM-score 0.99, RMSD 0.33 Å
- 7MRX chain A against the predicted model P00648: TM-score 0.99, RMSD 0.31 Å
- 1BNS chain A against the predicted model P00648: TM-score 0.99, RMSD 0.32 Å
Elsewhere
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