Research workbench
Crystal structure of EV71 rdrp in complex with GTP
Analyse Crystal structure of EV71 rdrp in complex with GTP in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3N6M
- Type
- protein
- Length
- 462 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA-dependent RNA polymerase
- UniProt
- D3K0N8
- Ligands
- GTP, NI
- Pockets
- 4 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA-dependent RNA polymerase | protein | 462 | 42% helix, 16% strand | D3K0N8 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 361 | 0.73 | 0.84 | 52 | empty |
| 2 | 360 | 0.56 | 0.75 | 37 | GTP |
| 3 | 202 | 0.50 | 0.76 | 28 | empty |
| 4 | 96 | 0.37 | 0.75 | 18 | empty |
Compared structures
- 3N6M · Crystal structure of EV71 RdRp in complex with GTP · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D3K0N8
- Elsewhere: RCSB PDB 3N6M · PDBe 3N6M · UniProt D3K0N8
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