Research workbench
Pig gastric H+/K+-ATPase complexed with aluminium fluoride
Analyse Pig gastric H+/K+-ATPase complexed with aluminium fluoride in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3IXZ
- Type
- protein
- Length
- 1,044 residues
- Chains
- 2
- Method
- electron crystallography
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Potassium-transporting ATPase alpha; Potassium-transporting ATPase subunit beta
- EC
- 3.6.3.10
- UniProt
- P19156, P18434
- Pockets
- 5 · best druggability 0.53
Structure
electron crystallography · 2 distinct chains · 0% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Potassium-transporting ATPase alpha (EC 3.6.3.10) | protein | 998 | 0% helix, 0% strand | P19156 |
| B | Potassium-transporting ATPase subunit beta | protein | 46 | 0% helix, 0% strand | P18434 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 263 | 0.53 | 0.73 | 57 | empty |
| 2 | 197 | 0.49 | 0.74 | 47 | empty |
| 3 | 104 | 0.37 | 0.73 | 29 | empty |
| 4 | 83 | 0.34 | 0.73 | 24 | empty |
| 5 | 59 | 0.31 | 0.73 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 42 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 3IXZ · Pig gastric H+/K+-ATPase complexed with aluminium fluoride · the same entry in another collection · chain A against A, TM-score 1.00
- P19156 · AlphaFold monomer V2.0 prediction for potassium-transporting ATPase alpha chain 1 (P19156) · a predicted model of the same protein · chain A against A, TM-score 0.97
- P18434 · AlphaFold monomer V2.0 prediction for potassium-transporting ATPase subunit beta (P18434) · a predicted model of the same protein · chain B against A, TM-score 0.77
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P19156
- Every structure of UniProt P18434
- Elsewhere: RCSB PDB 3IXZ · PDBe 3IXZ · UniProt P19156 · UniProt P18434
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.