Research workbench
Crystal structure of the tandem tudor domains of the E3 ubiquitin- protein ligase UHRF1 in complex with trimethylated histone H3-K9 peptide
Analyse Crystal structure of the tandem tudor domains of the E3 ubiquitin- protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3DB3
- Type
- protein
- Length
- 143 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- E3 ubiquitin-protein ligase UHRF1; Trimethylated histone H3-K9 peptide
- EC
- 6.3.2.-
- UniProt
- Q96T88, Q71DI3
Structure
x-ray diffraction · 2 distinct chains · 6% helix, 46% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) | protein | 140 | 6% helix, 47% strand | Q96T88 |
| B | Trimethylated histone H3-K9 peptide | protein | 3 | 0% helix, 0% strand | Q71DI3 |
Interfaces
1 interface between chains.
- A–B · 272 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 4 modified (engineered, methylation).
Compared structures
- 3DB3 · Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 in… · the same entry in another collection · chain A against A, TM-score 1.00
- Q71DI3 · AlphaFold monomer V2.0 prediction for histone H3.2 (Q71DI3) · a predicted model of the same protein · chain B against A, TM-score 1.00
- Q96T88 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase UHRF1 (Q96T88) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96T88
- Every structure of UniProt Q71DI3
- Elsewhere: RCSB PDB 3DB3 · PDBe 3DB3 · UniProt Q96T88 · UniProt Q71DI3
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