UniProt Q71DI3
Histone H3.2 (Q71DI3)
Histone H3.2 (UniProt Q71DI3): 93 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 245 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q71DI3
- Protein
- Histone H3.2
- Experimental structures
- 93
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 245 · 22 records with a druggable one
Structures
94 records of Q71DI3 in the MolNFT archive: 93 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2X4W | Molecular basis of Histone H3K36me3 recognition by the PWWP domain of BRPF1. | x-ray diffraction | B | — | — |
| 2X4W | Molecular basis of histone H3K36ME3 recognition by the pwwp domain of BRPF1. | x-ray diffraction | B | — | — |
| 2X4X | Molecular basis of Histone H3K36me3 recognition by the PWWP domain of BRPF1. | x-ray diffraction | B, D, F, H | — | — |
| 2X4X | Molecular basis of histone H3K36ME3 recognition by the pwwp domain of BRPF1. | x-ray diffraction | B, D, F, H | — | — |
| 2X4Y | Molecular basis of Histone H3K36me3 recognition by the PWWP domain of BRPF1. | x-ray diffraction | B, D, F, H, J, L, N, P | — | — |
| 2X4Y | Molecular basis of histone H3K36ME3 recognition by the pwwp domain of BRPF1. | x-ray diffraction | B, D, F, H, J, L, N, P | — | — |
| 3AV1 | The human nucleosome structure containing the histone variant H3.2 | x-ray diffraction | A, E | — | — |
| 3AV1 | The human nucleosome structure containing the histone variant H3.2 | x-ray diffraction | A, E | — | — |
| 3DB3 | Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 in complex… | x-ray diffraction | B | — | — |
| 3DB3 | Crystal structure of the tandem tudor domains of the E3 ubiquitin- protein ligase UHRF1 in complex… | x-ray diffraction | B | — | — |
| 3MO8 | PWWP Domain of Human Bromodomain and PHD finger-containing protein 1 In Complex with Trimethylated… | x-ray diffraction | B | — | — |
| 3MO8 | Pwwp domain of human bromodomain and phd finger-containing protein 1 in complex with trimethylated… | x-ray diffraction | B | — | — |
| 4MZF | Crystal structure of human Spindlin1 bound to histone H3(K4me3-R8me2a) peptide | x-ray diffraction | A | — | — |
| 4MZF | Crystal structure of human SPINDLIN1 bound to histone H3(K4ME3-R8ME2A) peptide | x-ray diffraction | A | — | — |
| 4MZG | Crystal structure of human Spindlin1 bound to histone H3K4me3 peptide | x-ray diffraction | A, C | — | — |
| 4MZG | Crystal structure of human SPINDLIN1 bound to histone H3K4ME3 peptide | x-ray diffraction | A, C | — | — |
| 4MZH | Crystal structure of human Spindlin1 bound to histone H3(K4me3-R8me2s) peptide | x-ray diffraction | B | — | — |
| 4MZH | Crystal structure of human SPINDLIN1 bound to histone H3(K4ME3-R8ME2S) peptide | x-ray diffraction | B | — | — |
| 4OUC | Structure of human haspin in complex with histone H3 substrate | x-ray diffraction | B | — | — |
| 4OUC | Structure of human haspin in complex with histone H3 substrate | x-ray diffraction | B | — | — |
| 5B0Y | Crystal structure of the nucleosome containing histone H3 with the crotonylated lysine 122 | x-ray diffraction | A, E | — | — |
| 5B0Z | The crystal structure of the nucleosome containing H3.2, at 1.98 A resolution | x-ray diffraction | A, E | — | — |
| 5B0Z | The crystal structure of the nucleosome containing H3.2, at 1.98 a resolution | x-ray diffraction | A, E | — | — |
| 5B40 | The nucleosome structure containing H2B-K120 and H4-K31 monoubiquitinations | x-ray diffraction | A, E | — | 9 (best 0.75) |
| 5B40 | The nucleosome structure containing H2B-K120 and H4-K31 monoubiquitinations | x-ray diffraction | A, E | — | — |
| 5BO0 | Crystal structure of Human MCM2 HBD and ASF1b chaperoning a histone H3.2-H4 dimer | x-ray diffraction | A | — | — |
| 5BO0 | Crystal structure of human MCM2 hbd and ASF1B chaperoning a histone H3.2-H4 dimer | x-ray diffraction | A | — | — |
| 5VAC | Crystal structure of ATXR5 set domain in complex with K36ME3 histone H3 peptide | x-ray diffraction | C | — | — |
| 6FML | Cryoem structure INO80CORE nucleosome complex | electron microscopy | M, Q | — | — |
| 6T79 | Structure of a human nucleosome at 3.2 a resolution | electron microscopy | A, E | — | — |
| 6T7A | Structure of human SOX11 transcription factor in complex with a nucleosome | electron microscopy | A, E | — | — |
| 6T7B | Structure of human Sox2 transcription factor in complex with a nucleosome | electron microscopy | A, E | — | 10 (best 0.64) |
| 6T7B | Structure of human SOX2 transcription factor in complex with a nucleosome | electron microscopy | A, E | — | — |
| 6T7C | Structure of two copies of human SOX11 transcription factor in complex with a nucleosome | electron microscopy | A, E | — | — |
| 6T7D | Structure of human SOX11 transcription factor in complex with a nucleosome | electron microscopy | A, E | — | — |
| 6X59 | The mouse cgas catalytic domain binding to human assembled nucleosome | electron microscopy | A, E | — | — |
| 6X5A | The mouse cgas catalytic domain binding to human nucleosome that purified from HEK293T cells | electron microscopy | A, E | — | — |
| 6XJD | Two mouse cGAS catalytic domain binding to human assembled nucleosome | electron microscopy | A, E | — | — |
| 6XJD | Two mouse cgas catalytic domain binding to human assembled nucleosome | electron microscopy | A, E | — | — |
| 6Y5D | Structure of human cGAS (K394E) bound to the nucleosome | electron microscopy | A, E, M, Q | PTD | — |
| 6Y5D | Structure of human cgas (K394E) bound to the nucleosome | electron microscopy | A, E, M, Q | PTD | — |
| 6Y5E | Structure of human cGAS (K394E) bound to the nucleosome (focused refinement of cGAS-NCP subcomplex) | electron microscopy | A, E | PTD | 10 (best 0.74) |
| 6Y5E | Structure of human cgas (K394E) bound to the nucleosome (focused refinement of cgas-ncp subcomplex) | electron microscopy | A, E | PTD | — |
| 7BQZ | Crystal structure of SPINDLIN1 bound to H3(K4ME3-K9ME3) peptide | x-ray diffraction | B, D, F, H | — | — |
| 7BU9 | Crystal Structure of Spindlin1-H3(K4me3-K9me2) complex | x-ray diffraction | B, D, F, H | — | — |
| 7BU9 | Crystal structure of SPINDLIN1-H3(K4ME3-K9ME2) complex | x-ray diffraction | B, D, F, H | — | — |
| 7JO9 | 1:1 cgas-nucleosome complex | electron microscopy | A, E | — | — |
| 7JOA | 2:1 cgas-nucleosome complex | electron microscopy | A, E | — | — |
| 7JZV | Cryo-EM structure of the BRCA1-UBCH5C/BARD1 E3-E2 module bound to a nucleosome | electron microscopy | P, p | — | — |
| 7PET | The 4x177 nucleosome array containing H1 | electron microscopy | A, E, a, e, K, O, k, o | — | 13 (best 0.82) |
| 7PET | The 4X177 nucleosome array containing H1 | electron microscopy | A, E, a, e, K, O, k, o | — | — |
| 7PEU | Trinucleosome of the 4X177 nucleosome array containing H1 | electron microscopy | A, E, a, e, K, O | — | — |
| 7PEV | Nucleosome stack of the 4x177 nucleosome array containing H1 | electron microscopy | A, E, K, O | — | 8 (best 0.78) |
| 7PEV | Nucleosome stack of the 4X177 nucleosome array containing H1 | electron microscopy | A, E, K, O | — | — |
| 7PEW | Nucleosome 1 of the 4x177 nucleosome array containing H1 | electron microscopy | A, E | — | 11 (best 0.76) |
| 7PEW | Nucleosome 1 of the 4X177 nucleosome array containing H1 | electron microscopy | A, E | — | — |
| 7PEX | Nucleosome 2 of the 4X177 nucleosome array containing H1 | electron microscopy | a, e | — | — |
| 7PEY | Nucleosome 3 of the 4x177 nucleosome array containing H1 | electron microscopy | K, O | — | 11 (best 0.82) |
| 7PEY | Nucleosome 3 of the 4X177 nucleosome array containing H1 | electron microscopy | K, O | — | — |
| 7PEZ | Nucleosome 4 of the 4X177 nucleosome array containing H1 | electron microscopy | k, o | — | — |
34 records more on the page itself.
Ligands
Experiment against prediction
- 3DB3 chain B against the predicted model Q71DI3: TM-score 1.00, RMSD 0.02 Å
- 3DB3 chain B against the predicted model Q71DI3: TM-score 1.00, RMSD 0.02 Å
- 8JLB chain E against the predicted model Q71DI3: TM-score 0.99, RMSD 0.28 Å
- 5B0Y chain A against the predicted model Q71DI3: TM-score 0.99, RMSD 0.29 Å
- 3AV1 chain A against the predicted model Q71DI3: TM-score 0.99, RMSD 0.29 Å
- 3AV1 chain A against the predicted model Q71DI3: TM-score 0.99, RMSD 0.29 Å
- 8JLD chain A against the predicted model Q71DI3: TM-score 0.99, RMSD 0.30 Å
- 8JLB chain A against the predicted model Q71DI3: TM-score 0.99, RMSD 0.30 Å
- 8JLD chain E against the predicted model Q71DI3: TM-score 0.99, RMSD 0.30 Å
- 6Y5E chain A against the predicted model Q71DI3: TM-score 0.99, RMSD 0.31 Å
Elsewhere
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