Research workbench
Bovine purine nucleoside phosphorylase complexed with 9-deazainosine and phosphate
Analyse Bovine purine nucleoside phosphorylase complexed with 9-deazainosine and… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1A9P
- Type
- protein
- Length
- 289 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Purine nucleoside phosphorylase
- EC
- 2.4.2.1
- UniProt
- P55859
- Ligands
- 9DI, PO4
- Pockets
- 3 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Purine nucleoside phosphorylase (EC 2.4.2.1) | protein | 289 | 32% helix, 23% strand | P55859 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 130 | 0.65 | 0.87 | 25 | PO4, 9DI |
| 2 | 94 | 0.64 | 0.89 | 21 | empty |
| 3 | 51 | 0.33 | 0.78 | 15 | empty |
Compared structures
- 1A9P · Bovine purine nucleoside phosphorylase complexed with 9-deazainosine and phosphate · the same entry in another collection · chain A against A, TM-score 1.00
- P55859 · AlphaFold monomer V2.0 prediction for purine nucleoside phosphorylase (P55859) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P55859
- Elsewhere: RCSB PDB 1A9P · PDBe 1A9P · UniProt P55859
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