Research workbench
Crystallographic structure of GM23 an example of catalytic migration from tim to thiamin phosphate synthase.
Analyse Crystallographic structure of GM23 an example of catalytic migration from tim… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2Y6Z
- Type
- protein
- Length
- 256 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Triose-phosphate isomerase
- EC
- 5.3.1.1
- UniProt
- P04789
- Ligands
- TPS, POP
- Pockets
- 2 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Triose-phosphate isomerase (EC 5.3.1.1) | protein | 256 | 45% helix, 16% strand | P04789 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 184 | 0.54 | 0.79 | 29 | TPS |
| 2 | 95 | 0.39 | 0.76 | 18 | empty |
Compared structures
- 2Y6Z · Crystallographic structure of GM23 an example of Catalytic migration from TIM to thiamin… · the same entry in another collection · chain A against A, TM-score 1.00
- 4TIM · Crystallographic and molecular modeling studies on trypanosomal triosephosphate… · a predicted model of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04789
- Elsewhere: RCSB PDB 2Y6Z · PDBe 2Y6Z · UniProt P04789
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.