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Crystal structure of fibrillin-1 domains CBEGF9HYB2CBEGF10, calcium saturated form

Analyse Crystal structure of fibrillin-1 domains CBEGF9HYB2CBEGF10, calcium saturated… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2W86
Type: protein
Length: 147 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fibrillin-1
UniProt: P35555
Ligands: CA, IOD
Pockets: 1 · best druggability 0.51

Structure

x-ray diffraction · 1 distinct chain · 9% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fibrillin-1	protein	147	9% helix, 41% strand	P35555

Ligands and binding sites

CA · Calcium ion · metal · 2 copies · chains A
IOD · Iodide ion · ion · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	157	0.51	0.79	28	empty

Modifications

Observed in the structure: 10 disulfide (disulfide).

Compared structures

2W86 · Crystal structure of fibrillin-1 domains cbEGF9hyb2cbEGF10, calcium saturated form · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P35555
Elsewhere: RCSB PDB 2W86 · PDBe 2W86 · UniProt P35555

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