Structure of mouse A1 bound to the bak BH3-domain

Structure

x-ray diffraction · 2 distinct chains · 77% helix, 0% strand (DSSP).

Ligands and binding sites

• SO4 · Sulfate ion · ion · chains A, B
• CIT · Citric acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 1000 Ų buried · 11 hydrogen bonds · protein-protein

Compared structures

• 2VOH · Structure of mouse A1 bound to the Bak BH3-domain · the same entry in another collection · chain A against A, TM-score 1.00
• Q07440 · AlphaFold monomer V2.0 prediction for BCL-2-related protein A1 (Q07440) · a predicted model of the same protein · chain A against A, TM-score 0.90
• O08734 · AlphaFold monomer V2.0 prediction for BCL-2 homologous ANTAGONIST/KILLER (O08734) · a predicted model of the same protein · chain B against A, TM-score 0.80

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q07440
• Every structure of UniProt O08734
• Elsewhere: RCSB PDB 2VOH · PDBe 2VOH · UniProt Q07440 · UniProt O08734