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Structure of APPBP1-UBA3~NEDD8-NEDD8-mgatp-UBC12(C111A), a trapped ubiquitin-like protein activation complex

Analyse Structure of APPBP1-UBA3~NEDD8-NEDD8-mgatp-UBC12(C111A), a trapped… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2NVU
Type
protein
Length
1,647 residues
Chains
5
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q13564, Q8TBC4, P61081, Q15843

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein530—Q13564
B—protein789—Q8TBC4
C—protein176—P61081
I, J—protein76—Q15843

Compared structures

  • 2NVU · Structure of APPBP1-UBA3~NEDD8-NEDD8-MgATP-Ubc12(C111A), a trapped ubiquitin-like protein… · the same entry in another collection · chain J against J, TM-score 1.00
  • Q13564 · AlphaFold monomer V2.0 prediction for NEDD8-activating enzyme E1 regulatory subunit… · a predicted model of the same protein · chain A against A, TM-score 0.99
  • P61081 · AlphaFold monomer V2.0 prediction for NEDD8-conjugating enzyme UBC12 (P61081) · a predicted model of the same protein · chain C against A, TM-score 0.92
  • Q15843 · AlphaFold monomer V2.0 prediction for NEDD8 (Q15843) · a predicted model of the same protein · chain I against A, TM-score 0.90
  • Q8TBC4 · AlphaFold monomer V2.0 prediction for NEDD8-activating enzyme E1 catalytic subunit… · a predicted model of the same protein · chain B against A, TM-score 0.46

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