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Structure of the integrin alphaiib-BETA3(A711P) transmembrane complex

Analyse Structure of the integrin alphaiib-BETA3(A711P) transmembrane complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2N9Y
Type: protein
Length: 85 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Integrin alpha-iib; Integrin beta-3
UniProt: P08514, P05106

Structure

solution nmr · 2 distinct chains · 66% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Integrin alpha-iib	protein	42	57% helix, 0% strand	P08514
B	Integrin beta-3	protein	43	74% helix, 0% strand	P05106

Interfaces

1 interface between chains.

A–B · 892 Å² buried · 3 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

2N9Y · Structure of the Integrin alphaIIb-beta3(A711P) Transmembrane Complex · the same entry in another collection · chain A against A, TM-score 1.00
P08514 · AlphaFold monomer V2.0 prediction for integrin alpha-iib (P08514) · a predicted model of the same protein · chain A against A, TM-score 0.73

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08514
Every structure of UniProt P05106
Elsewhere: RCSB PDB 2N9Y · PDBe 2N9Y · UniProt P08514 · UniProt P05106

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