Research workbench

NMR structure of a human CALMODULIN/CONNEXIN-36 peptide hybrid

Analyse NMR structure of a human CALMODULIN/CONNEXIN-36 peptide hybrid in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2N6A
Type: protein
Length: 162 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Human CALMODULIN/CONNEXIN-36 peptide hybrid
UniProt: P62158, Q9UKL4
Ligands: CA
Pockets: 2 · best druggability 0.46

Structure

solution nmr · 1 distinct chain · 58% helix, 5% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Human CALMODULIN/CONNEXIN-36 peptide hybrid	protein	162	58% helix, 5% strand	P62158, Q9UKL4

Ligands and binding sites

CA · Calcium ion · metal · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	82	0.46	0.81	24	empty
2	74	0.41	0.79	17	empty

Compared structures

2N6A · NMR structure of a human calmodulin/connexin-36 peptide hybrid · the same entry in another collection · chain A against A, TM-score 1.00
Q9UKL4 · AlphaFold monomer V2.0 prediction for gap junction delta-2 protein (Q9UKL4) · a predicted model of the same protein · chain A against A, TM-score 0.29

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P62158
Every structure of UniProt Q9UKL4
Elsewhere: RCSB PDB 2N6A · PDBe 2N6A · UniProt P62158 · UniProt Q9UKL4

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