Research workbench
NMR structure of the C-domain of troponin C bound to the anchoring region of troponin I
Analyse NMR structure of the C-domain of troponin C bound to the anchoring region of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2MLE
- Type
- protein
- Length
- 72 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Troponin C, slow skeletal and cardiac muscles
- UniProt
- P63316
- Ligands
- CA
- Pockets
- 1 · best druggability 0.34
Structure
solution nmr · 1 distinct chain · 58% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C | Troponin C, slow skeletal and cardiac muscles | protein | 72 | 58% helix, 3% strand | P63316 |
Ligands and binding sites
- CA · Calcium ion · metal · 2 copies · chains C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 57 | 0.34 | 0.77 | 10 | empty |
Compared structures
- 2MLE · NMR structure of the C-domain of troponin C bound to the anchoring region of troponin I · the same entry in another collection · chain C against C, TM-score 1.00
- P63316 · AlphaFold monomer V2.0 prediction for troponin C, slow skeletal and cardiac muscles… · a predicted model of the same protein · chain C against A, TM-score 0.74
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63316
- Elsewhere: RCSB PDB 2MLE · PDBe 2MLE · UniProt P63316
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