The solution NMR structure of the complex between MNK1 and HAH1 mediated by CU(I)

Structure

solution nmr · 2 distinct chains · 30% helix, 31% strand (DSSP).

Ligands and binding sites

• CU · Copper (II) ion · metal · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 552 Ų buried · 10 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

• 2K1R · The solution NMR structure of the complex between MNK1 and HAH1 mediated by Cu(I) · the same entry in another collection · chain A against A, TM-score 1.00
• O00244 · AlphaFold monomer V2.0 prediction for copper transport protein ATOX1 (O00244) · a predicted model of the same protein · chain B against A, TM-score 0.93
• Q04656 · AlphaFold monomer V2.0 prediction for copper-transporting ATPase 1 (Q04656) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q04656
• Every structure of UniProt O00244
• Elsewhere: RCSB PDB 2K1R · PDBe 2K1R · UniProt Q04656 · UniProt O00244