Research workbench

Apo open form of GLUCOSE/GALACTOSE binding protein

Analyse Apo open form of GLUCOSE/GALACTOSE binding protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2FW0
Type: protein
Length: 305 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: D-galactose-binding periplasmic protein
UniProt: P0AEE5
Ligands: NA, CA
Pockets: 1 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 44% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	D-galactose-binding periplasmic protein	protein	305	44% helix, 19% strand	P0AEE5

Ligands and binding sites

NA · Sodium ion · metal · 3 copies · chains A
CA · Calcium ion · metal · chains A
CIT · Citric acid · additive · chains A
MLA · Malonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	302	0.55	0.75	33	NA, CIT

Compared structures

2FW0 · Apo Open Form of Glucose/Galactose Binding Protein · the same entry in another collection · chain A against A, TM-score 1.00
P0AEE5 · AlphaFold monomer V2.0 prediction for D-galactose-binding periplasmic protein (P0AEE5) · a predicted model of the same protein · chain A against A, TM-score 0.81

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0AEE5
Elsewhere: RCSB PDB 2FW0 · PDBe 2FW0 · UniProt P0AEE5

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