Research workbench
The crystal structure of rhob in the GDP-bound state
Analyse The crystal structure of rhob in the GDP-bound state in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2FV8
- Type
- protein
- Length
- 180 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Rho-related GTP-binding protein rhob
- UniProt
- P62745
- Ligands
- GDP
- Pockets
- 1 · best druggability 0.31
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Rho-related GTP-binding protein rhob | protein | 180 | 40% helix, 24% strand | P62745 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 66 | 0.31 | 0.74 | 13 | empty |
Compared structures
- 2FV8 · The crystal structure of RhoB in the GDP-bound state · the same entry in another collection · chain A against A, TM-score 1.00
- P62745 · AlphaFold monomer V2.0 prediction for rho-related GTP-binding protein rhob (P62745) · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62745
- Elsewhere: RCSB PDB 2FV8 · PDBe 2FV8 · UniProt P62745
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