UniProt P62745
Rho-related GTP-binding protein RhoB (P62745)
Rho-related GTP-binding protein RhoB (UniProt P62745): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P62745
- Protein
- Rho-related GTP-binding protein RhoB
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 7 · 2 records with a druggable one
Structures
7 records of P62745 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2FV8 | The crystal structure of RhoB in the GDP-bound state | x-ray diffraction | A | — | — |
| 2FV8 | The crystal structure of rhob in the GDP-bound state | x-ray diffraction | A | — | — |
| 6HXU | Crystal structure of Human RHOB Q63L in complex with GTP | x-ray diffraction | A | GTP, MG | — |
| 6HXU | Crystal structure of human rhob Q63L in complex with GTP | x-ray diffraction | A | GTP, MG | — |
| 6SGE | Crystal structure of Human RHOB-GTP in complex with nanobody B6 | x-ray diffraction | A, C | GTP, MG | 6 (best 0.75) |
| 6SGE | Crystal structure of human rhob-GTP in complex with nanobody B6 | x-ray diffraction | A, C | GTP, MG | — |
| P62745 | AlphaFold monomer V2.0 prediction for rho-related GTP-binding protein rhob (P62745) | predicted | A | — | 1 (best 0.54) |
Ligands
Experiment against prediction
- 6SGE chain A against the predicted model P62745: TM-score 0.99, RMSD 0.50 Å
- 6SGE chain A against the predicted model P62745: TM-score 0.99, RMSD 0.50 Å
- 6HXU chain A against the predicted model P62745: TM-score 0.98, RMSD 0.68 Å
- 6HXU chain A against the predicted model P62745: TM-score 0.98, RMSD 0.68 Å
- 6SGE chain C against the predicted model P62745: TM-score 0.98, RMSD 0.85 Å
- 6SGE chain C against the predicted model P62745: TM-score 0.98, RMSD 0.85 Å
- 2FV8 chain A against the predicted model P62745: TM-score 0.92, RMSD 1.61 Å
- 2FV8 chain A against the predicted model P62745: TM-score 0.92, RMSD 1.61 Å
Elsewhere
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