Crystal structure of the complex between the C-terminal domains of human xpf and ERCC1

Structure

x-ray diffraction · 2 distinct chains · 64% helix, 0% strand (DSSP).

Ligands and binding sites

• HG · Mercury (II) ion · metal · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 1149 Ų buried · 7 hydrogen bonds · protein-protein

Compared structures

• 2A1J · Crystal Structure of the Complex between the C-Terminal Domains of Human XPF and ERCC1 · the same entry in another collection · chain A against A, TM-score 1.00
• Q92889 · AlphaFold monomer V2.0 prediction for DNA repair endonuclease xpf (Q92889) · a predicted model of the same protein · chain A against A, TM-score 0.90
• P07992 · AlphaFold monomer V2.0 prediction for DNA excision repair protein ercc-1 (P07992) · a predicted model of the same protein · chain B against A, TM-score 0.80

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q92889
• Every structure of UniProt P07992
• Elsewhere: RCSB PDB 2A1J · PDBe 2A1J · UniProt Q92889 · UniProt P07992