UniProt P07992
DNA excision repair protein ERCC-1 (P07992)
DNA excision repair protein ERCC-1 (UniProt P07992): 16 experimental structures and 1 predicted model on GenesisL1, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P07992
- Protein
- DNA excision repair protein ERCC-1
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 10 · 2 records with a druggable one
Structures
17 records of P07992 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1Z00 | Solution structure of the C-terminal domain of ERCC1 complexed with the C-terminal domain of XPF | solution nmr | A | — | — |
| 1Z00 | Solution structure of the C-terminal domain of ERCC1 complexed with the C-terminal domain of xpf | solution nmr | A | — | — |
| 2A1I | Crystal Structure of the Central Domain of Human ERCC1 | x-ray diffraction | A | — | — |
| 2A1I | Crystal structure of the central domain of human ERCC1 | x-ray diffraction | A | — | — |
| 2A1J | Crystal Structure of the Complex between the C-Terminal Domains of Human XPF and ERCC1 | x-ray diffraction | B | — | — |
| 2A1J | Crystal structure of the complex between the C-terminal domains of human xpf and ERCC1 | x-ray diffraction | B | — | — |
| 2JNW | Solution structure of a ERCC1-XPA heterodimer | solution nmr | A | — | — |
| 2JNW | Solution structure of a ERCC1-xpa heterodimer | solution nmr | A | — | — |
| 2JPD | Solution structure of the ERCC1 central domain | solution nmr | A | — | — |
| 2JPD | Solution structure of the ERCC1 central domain | solution nmr | A | — | — |
| 2MUT | Solution structure of the F231L mutant ERCC1-XPF dimerization region | solution nmr | A | — | — |
| 2MUT | Solution structure of the F231L mutant ERCC1-xpf dimerization region | solution nmr | A | — | — |
| 6SXA | XPF-ERCC1 Cryo-EM Structure, Apo-form | electron microscopy | G | — | 6 (best 0.83) |
| 6SXA | Xpf-ERCC1 cryo-EM structure, apo-form | electron microscopy | G | — | — |
| 6SXB | XPF-ERCC1 Cryo-EM Structure, DNA-Bound form | electron microscopy | G | — | 4 (best 0.73) |
| 6SXB | Xpf-ERCC1 cryo-EM structure, DNA-bound form | electron microscopy | G | — | — |
| P07992 | AlphaFold monomer V2.0 prediction for DNA excision repair protein ercc-1 (P07992) | predicted | A | — | — |
Experiment against prediction
- 2JNW chain A against the predicted model P07992: TM-score 0.97, RMSD 0.77 Å
- 2JNW chain A against the predicted model P07992: TM-score 0.97, RMSD 0.77 Å
- 2JPD chain A against the predicted model P07992: TM-score 0.92, RMSD 1.47 Å
- 2JPD chain A against the predicted model P07992: TM-score 0.92, RMSD 1.47 Å
- 2A1I chain A against the predicted model P07992: TM-score 0.91, RMSD 1.24 Å
- 2A1I chain A against the predicted model P07992: TM-score 0.91, RMSD 1.24 Å
- 2A1J chain B against the predicted model P07992: TM-score 0.80, RMSD 1.35 Å
- 2A1J chain B against the predicted model P07992: TM-score 0.80, RMSD 1.35 Å
- 1Z00 chain A against the predicted model P07992: TM-score 0.72, RMSD 1.75 Å
- 1Z00 chain A against the predicted model P07992: TM-score 0.72, RMSD 1.75 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.