Research workbench
Crystal structures of SULT1A2 and SULT1A1*3: implications in the bioactivation of N-hydroxy-2-acetylamino fluorine (oh-aaf)
Analyse Crystal structures of SULT1A2 and SULT1A1*3: implications in the bioactivation… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1Z29
- Type
- protein
- Length
- 281 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phenol-sulfating phenol sulfotransferase 2
- EC
- 2.8.2.1
- UniProt
- P50226
- Ligands
- A3P, CA
- Pockets
- 1 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phenol-sulfating phenol sulfotransferase 2 (EC 2.8.2.1) | protein | 281 | 42% helix, 11% strand | P50226 |
Ligands and binding sites
- A3P · Adenosine-3'-5'-diphosphate · ligand · chains A
- CA · Calcium ion · metal · chains A
- ACY · Acetic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 323 | 0.83 | 0.93 | 57 | CA, A3P, ACY |
Compared structures
- 1Z29 · Crystal Structures of SULT1A2 and SULT1A1*3: Implications in the bioactivation of… · the same entry in another collection · chain A against A, TM-score 1.00
- P50226 · AlphaFold monomer V2.0 prediction for sulfotransferase 1A2 (P50226) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P50226
- Elsewhere: RCSB PDB 1Z29 · PDBe 1Z29 · UniProt P50226
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.