Dianhydrosugar-based benzamidine, factor xa specific inhibitor in complex with bovine trypsin mutant

Structure

x-ray diffraction · 1 distinct chain · 10% helix, 36% strand (DSSP).

Ligands and binding sites

• TL3 · 2,5-bis-O-{4-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-D-glucitol · ligand · chains T
• CA · Calcium ion · metal · chains T
• SO4 · Sulfate ion · ion · 2 copies · chains T
• IMD · Imidazole · additive · chains T

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

• 1Y5B · Dianhydrosugar-based benzamidine, factor Xa specific inhibitor in complex with bovine… · the same entry in another collection · chain T against T, TM-score 1.00
• 1TNH · Prediction of novel serine protease inhibitors · a predicted model of the same protein · chain T against A, TM-score 1.00
• 1TNL · Prediction of novel serine protease inhibitors · a predicted model of the same protein · chain T against A, TM-score 1.00
• 1TNJ · Prediction of novel serine protease inhibitors · a predicted model of the same protein · chain T against A, TM-score 1.00
• 1TNK · Prediction of novel serine protease inhibitors · a predicted model of the same protein · chain T against A, TM-score 1.00
• 1TNG · Prediction of novel serine protease inhibitors · a predicted model of the same protein · chain T against A, TM-score 1.00
• 1TNI · Prediction of novel serine protease inhibitors · a predicted model of the same protein · chain T against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P00760
• Elsewhere: RCSB PDB 1Y5B · PDBe 1Y5B · UniProt P00760