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Crystal structure of mlam mutant of dimerisation domain of nf-kb P50 transcription factor

Analyse Crystal structure of mlam mutant of dimerisation domain of nf-kb P50… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1U42
Type: protein
Length: 101 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nuclear factor nf-kappa-B P105 subunit
UniProt: P25799
Pockets: 1 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 0% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nuclear factor nf-kappa-B P105 subunit	protein	101	0% helix, 24% strand	P25799

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	342	0.56	0.75	40	empty

Compared structures

1U42 · Crystal structure of MLAM mutant of dimerisation domain of NF-kB p50 transcription factor · the same entry in another collection · chain A against A, TM-score 1.00
P25799 · AlphaFold monomer V2.0 prediction for nuclear factor nf-kappa-B P105 subunit (P25799) · a predicted model of the same protein · chain A against A, TM-score 0.63

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P25799
Elsewhere: RCSB PDB 1U42 · PDBe 1U42 · UniProt P25799

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