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Crystal structure of bovine trypsinogen at 1.8 ångströms resolution. II. crystallographic refinement, refined crystal structure and comparison with bovine trypsin

Analyse Crystal structure of bovine trypsinogen at 1.8 ångströms resolution. II.… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1TGB
Type: protein
Length: 223 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Trypsinogen
UniProt: P00760
Ligands: CA
Pockets: 1 · best druggability 0.37

Structure

x-ray diffraction · 1 distinct chain · 10% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Trypsinogen	protein	223	10% helix, 35% strand	P00760

Ligands and binding sites

CA · Calcium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	50	0.37	0.80	18	empty

Modifications

Observed in the structure: 5 disulfide (disulfide).

Compared structures

1TGB · Crystal structure of bovine trypsinogen at 1.8 ångströms resolution. II. crystallographic… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00760
Elsewhere: RCSB PDB 1TGB · PDBe 1TGB · UniProt P00760

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