Research workbench
Crystal structure of the S1 domain of RNase E from E. COLI (pb derivative)
Analyse Crystal structure of the S1 domain of RNase E from E. COLI (pb derivative) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1SN8
- Type
- protein
- Length
- 167 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribonuclease E
- EC
- 3.1.4.-
- UniProt
- P21513
- Ligands
- PB
- Pockets
- 1 · best druggability 0.51
Structure
x-ray diffraction · 2 distinct chains · 15% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribonuclease E (EC 3.1.4.-) | protein | 87 | 14% helix, 36% strand | P21513 |
| B | Ribonuclease E (EC 3.1.4.-) | protein | 80 | 16% helix, 39% strand | P21513 |
Ligands and binding sites
- PB · Lead (II) ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 211 | 0.51 | 0.76 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 698 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 1SN8 · Crystal structure of the S1 domain of RNase E from E. coli (Pb derivative) · the same entry in another collection · chain A against A, TM-score 1.00
- P21513 · AlphaFold monomer V2.0 prediction for ribonuclease E (P21513) · a predicted model of the same protein · chain B against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21513
- Elsewhere: RCSB PDB 1SN8 · PDBe 1SN8 · UniProt P21513
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.