UniProt P21513
Ribonuclease E (P21513)
Ribonuclease E (UniProt P21513), EC 3.1.26.12: 28 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 53 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P21513
- Protein
- Ribonuclease E
- EC
- 3.1.26.12
- Experimental structures
- 28
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 53 · 5 records with a druggable one
Structures
29 records of P21513 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1SLJ | Solution structure of the S1 domain of RNase E from E. coli | solution nmr | A | — | — |
| 1SLJ | Solution structure of the S1 domain of RNase E from E. COLI | solution nmr | A | — | — |
| 1SMX | Crystal structure of the S1 domain of RNase E from E. coli (native) | x-ray diffraction | A, B | — | — |
| 1SMX | Crystal structure of the S1 domain of RNase E from E. COLI (native) | x-ray diffraction | A, B | — | — |
| 1SN8 | Crystal structure of the S1 domain of RNase E from E. coli (Pb derivative) | x-ray diffraction | A, B | — | — |
| 1SN8 | Crystal structure of the S1 domain of RNase E from E. COLI (pb derivative) | x-ray diffraction | A, B | — | — |
| 2BX2 | Catalytic domain of E. coli RNase E | x-ray diffraction | L | — | — |
| 2BX2 | Catalytic domain of E. COLI RNase E | x-ray diffraction | L | — | — |
| 2C0B | Catalytic domain of E. coli RNase E in complex with 13-mer RNA | x-ray diffraction | L | — | — |
| 2C0B | Catalytic domain of E. COLI RNase E in complex with 13-mer RNA | x-ray diffraction | L | — | — |
| 2C4R | Catalytic domain of E. coli RNase E | x-ray diffraction | L | — | — |
| 2C4R | Catalytic domain of E. COLI RNase E | x-ray diffraction | L | — | — |
| 2FYM | Crystal structure of E. coli enolase complexed with the minimal binding segment of RNase E. | x-ray diffraction | B, E | — | — |
| 2FYM | Crystal structure of E. COLI enolase complexed with the minimal binding segment of RNase E. | x-ray diffraction | B, E | — | — |
| 2VMK | Crystal Structure of E. coli RNase E Apoprotein - Catalytic Domain | x-ray diffraction | A, B, C, D | — | — |
| 2VMK | Crystal structure of E. COLI RNase E apoprotein - catalytic domain | x-ray diffraction | A, B, C, D | — | — |
| 2VRT | Crystal Structure of E. coli RNase E possessing M1 RNA fragments - Catalytic Domain | x-ray diffraction | A, B, C, D | — | — |
| 2VRT | Crystal structure of E. COLI RNase E possessing M1 RNA fragments - catalytic domain | x-ray diffraction | A, B, C, D | — | — |
| 3H1C | Crystal structure of Polynucleotide Phosphorylase (PNPase) core bound to RNase E and Tungstate | x-ray diffraction | D, E, F, H, J, L, N, P, S, U, W, Y | — | — |
| 3H1C | Crystal structure of polynucleotide phosphorylase (pnpase) core bound to RNase E and tungstate | x-ray diffraction | D, E, F, H, J, L, N, P, S, U, W, Y | — | — |
| 5F6C | The structure of E. coli RNase E catalytically inactive mutant with RNA bound | x-ray diffraction | A, B | — | — |
| 5F6C | The structure of E. coli RNase E catalytically inactive mutant with RNA bound | x-ray diffraction | A, B | MG, ZN | 15 (best 0.68) |
| 5F6C | The structure of E. COLI RNase E catalytically inactive mutant with RNA bound | x-ray diffraction | A, B | — | — |
| 5OHG | enolase in complex with RNase E | x-ray diffraction | C, J | — | 4 (best 0.79) |
| 5OHG | Enolase in complex with RNase E | x-ray diffraction | C, J | — | — |
| 6G63 | RNase E in complex with sRNA RrpA | x-ray diffraction | A, G, L, N | ZN, U | 20 (best 0.82) |
| 6G63 | RNase E in complex with srna rrpa | x-ray diffraction | A, G, L, N | ZN, U | — |
| 8B0J | CryoEM structure of bacterial RNaseE.RapZ.GlmZ complex central to the control of cell envelope… | electron microscopy | L, N | — | 9 (best 0.80) |
| P21513 | AlphaFold monomer V2.0 prediction for ribonuclease E (P21513) | predicted | A | — | 5 (best 0.80) |
Ligands
Experiment against prediction
- 2BX2 chain L against the predicted model P21513: TM-score 0.96, RMSD 1.24 Å
- 2BX2 chain L against the predicted model P21513: TM-score 0.96, RMSD 1.24 Å
- 2C0B chain L against the predicted model P21513: TM-score 0.96, RMSD 1.29 Å
- 2C0B chain L against the predicted model P21513: TM-score 0.96, RMSD 1.29 Å
- 6G63 chain L against the predicted model P21513: TM-score 0.95, RMSD 1.81 Å
- 6G63 chain L against the predicted model P21513: TM-score 0.95, RMSD 1.81 Å
- 2C4R chain L against the predicted model P21513: TM-score 0.95, RMSD 1.51 Å
- 2C4R chain L against the predicted model P21513: TM-score 0.95, RMSD 1.51 Å
- 6G63 chain N against the predicted model P21513: TM-score 0.95, RMSD 1.84 Å
- 6G63 chain N against the predicted model P21513: TM-score 0.95, RMSD 1.84 Å
Elsewhere
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