GL1X · GenesisL1 explorer

MolNFT v1 · #380684 · protein

AlphaFold monomer V2.0 prediction for ribonuclease E (P21513)

P21513: “AlphaFold monomer V2.0 prediction for ribonuclease E (P21513)”. 5 pockets (best druggability 0.80). MolNFT v1 #380684 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P21513
Type
protein
Length
1,061 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x4Dff1DBB225A3491870Fd31Ec92D348E5c96AE0b
Molecule
Ribonuclease E
UniProt
P21513
Pockets
5 · best druggability 0.80

Structure

1 distinct chain · 21% helix, 13% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARibonuclease Eprotein106121% helix, 13% strandP21513

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
110070.800.81105empty
23570.660.8044empty
31660.510.7824empty
4910.390.7719empty
5510.310.7615empty

Compared structures

  • 2BX2 · Catalytic domain of E. coli RNase E · an experimental structure of the same protein · chain A against L, TM-score 0.46
  • 2BX2 · Catalytic domain of E. COLI RNase E · an experimental structure of the same protein · chain A against L, TM-score 0.46
  • 6G63 · RNase E in complex with srna rrpa · an experimental structure of the same protein · chain A against N, TM-score 0.45
  • 6G63 · RNase E in complex with sRNA RrpA · an experimental structure of the same protein · chain A against N, TM-score 0.45
  • 2C4R · Catalytic domain of E. COLI RNase E · an experimental structure of the same protein · chain A against L, TM-score 0.45
  • 2C4R · Catalytic domain of E. coli RNase E · an experimental structure of the same protein · chain A against L, TM-score 0.45
  • 2C0B · Catalytic domain of E. coli RNase E in complex with 13-mer RNA · an experimental structure of the same protein · chain A against L, TM-score 0.45
  • 2C0B · Catalytic domain of E. COLI RNase E in complex with 13-mer RNA · an experimental structure of the same protein · chain A against L, TM-score 0.45

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