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PFS48/45 bound to Fab fragment of monoclonal antibody 10D8

Analyse PFS48/45 bound to Fab fragment of monoclonal antibody 10D8 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7ZXG
Type
protein
Length
1,574 residues
Chains
6
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q8I6T1
Ligands
NAG, BMA, MAN

Structure

x-ray diffraction · 6 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein363—Q8I6T1
B—protein218——
C—protein217——
D—protein352—Q8I6T1
E—protein215——
F—protein209——

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 12 copies · chains A, C, D, F
  • BMA · beta-D-mannopyranose · sugar · 2 copies · chains C
  • MAN · alpha-D-mannopyranose · sugar

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7ZXG · Pfs48/45 bound to Fab fragment of monoclonal antibody 10D8 · the same entry in another collection · chain F against F, TM-score 1.00
  • Q8I6T1 · AlphaFold monomer V2.0 prediction for gametocyte surface protein P45/48 (Q8I6T1) · a predicted model of the same protein · chain A against A, TM-score 0.86

Analyse

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