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Crystal structure of HIV-1 reverse transcriptase K103N/Y181C variant in complex with (E)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl) amino)-6-(3-morpholinopropoxy)-1,3,5-triazin-2-YL)AMINO)BENZONITRILE (JLJ564)
Analyse Crystal structure of HIV-1 reverse transcriptase K103N/Y181C variant in complex… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7SO3
- Type
- protein
- Length
- 937 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P03366
- Ligands
- 9W3, MG
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 537 | — | P03366 |
| B | — | protein | 400 | — | P03366 |
Ligands and binding sites
- 9W3 · 4-[(4-{4-[(E)-2-cyanoethenyl]-2,6-dimethylanilino}-6-[3-(morpholin-4-yl)propoxy]-1,3,5-triazin-2-yl) amino]benzonitrile · ligand · chains A, B
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7SO3 · Crystal Structure of HIV-1 Reverse Transcriptase K103N/Y181C Variant in Complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03366
- Elsewhere: RCSB PDB 7SO3 · PDBe 7SO3 · UniProt P03366
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