MolNFT v2 · #194472 · protein
Crystal Structure of HIV-1 Reverse Transcriptase K103N/Y181C Variant in Complex with (E)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)-6-(3-morpholinopropoxy)-1,3,5-triazin-2-yl)amino)benzonitrile (JLJ564)
7SO3: “Crystal Structure of HIV-1 Reverse Transcriptase K103N/Y181C Variant in Complex with…”. X-ray diffraction at 2.767, 2 ligands (9W3, MG). MolNFT v2 #194472 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7SO3
- Type
- protein
- Length
- 937 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.767
- Source
- Human immunodeficiency virus type 1 group M subtype B (isolate BH10)
- UniProt
- P03366
- Ligands
- 9W3, MG
Structure
x-ray diffraction · resolution 2.767 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 537 | — | P03366 |
| B | — | protein | 400 | — | P03366 |
Ligands and binding sites
- 9W3 · 4-[(4-{4-[(E)-2-cyanoethenyl]-2,6-dimethylanilino}-6-[3-(morpholin-4-yl)propoxy]-1,3,5-triazin-2-yl) amino]benzonitrile · ligand · chains A, B
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7SO3 · Crystal structure of HIV-1 reverse transcriptase K103N/Y181C variant in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03366
- Elsewhere: RCSB PDB 7SO3 · PDBe 7SO3 · UniProt P03366
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