Research workbench
Structure of tim-3 in complex with N-(4-(8-chloro-2-methyl-5-oxo-5,6- dihydro-[1,2,4]TRAIZOLO[1,5-C]QUINAZOLIN-9-yl)-3-methylphenyl)-1H- imidazole-2-sulfonamide (compound 38)
Analyse Structure of tim-3 in complex with N-(4-(8-chloro-2-methyl-5-oxo-5,6… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7M41
- Type
- protein
- Length
- 218 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8TDQ0
- Ligands
- YQG, CA
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 109 | — | Q8TDQ0 |
Ligands and binding sites
- YQG · N-{4-[(4s,10ap)-8-chloro-2-methyl-5-oxo-5,6-dihydro[1, 2,4]triazolo[1,5-c]quinazolin-9-yl]-3-methylphenyl}-1H-imidazole-2-sulfonamide · ligand · 2 copies · chains A, B
- CA · Calcium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7M41 · Structure of TIM-3 in complex with N-(4-(8-chloro-2-methyl-5-oxo-5,6-dihydro-[1,2,4]traizo… · the same entry in another collection · chain A against A, TM-score 1.00
- Q8TDQ0 · AlphaFold monomer V2.0 prediction for hepatitis a virus cellular receptor 2 (Q8TDQ0) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8TDQ0
- Elsewhere: RCSB PDB 7M41 · PDBe 7M41 · UniProt Q8TDQ0
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