Research workbench
Dihydropyrimidine dehydrogenase (dpd) C671A mutant soaked with uracil and NADPH anaerobically
Analyse Dihydropyrimidine dehydrogenase (dpd) C671A mutant soaked with uracil and NADPH… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7M32
- Type
- protein
- Length
- 4,045 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q28943
- Ligands
- SF4, FAD, URA, FNR
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 1012 | — | Q28943 |
| B | — | protein | 1011 | — | Q28943 |
| C | — | protein | 1008 | — | Q28943 |
| D | — | protein | 1014 | — | Q28943 |
Ligands and binding sites
- SF4 · Iron/sulfur cluster · ligand · 16 copies · chains A, B, C, D
- FAD · Flavin-adenine dinucleotide · ligand · 4 copies · chains A, B, C, D
- URA · Uracil · ligand · 4 copies · chains A, B, C, D
- FNR · 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydro-2H-benzo[g]pteridin-1-id-10(5H)-yl)-5-O-phosphonato-D-ribitol · ligand · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7M32 · Dihydropyrimidine Dehydrogenase (DPD) C671A Mutant Soaked with Uracil and NADPH… · the same entry in another collection · chain A against A, TM-score 1.00
- Q28943 · AlphaFold monomer V2.0 prediction for dihydropyrimidine dehydrogenase [NADP(+)] (Q28943) · a predicted model of the same protein · chain C against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q28943
- Elsewhere: RCSB PDB 7M32 · PDBe 7M32 · UniProt Q28943
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