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Ligand · FNR

FNR · 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydro-2H-benzo[g]pteridin-1-id-10(5H)-yl)-5-O-phosphonato-D-ribitol

FNR, 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydro-2H-benzo[g]pteridin-1-id-10(5H)-yl)-5-O-phosphonato-D-ribitol (C17 H23 N4 O9 P, 458.4 g/mol), in the MolNFT structures on GenesisL1: bound in 22 records (16 PDB entries). Every binding…

Component
FNR
Formula
C17 H23 N4 O9 P
Class
ligand
Structures
22
PDB entries
16

Binding sites

FNR in 22 structures; the first of them:

  • 5K9C · Crystal structure of human dihydroorotate dehydrogenase with ML390 · FNR A400 · binds ALA95, ALA96, GLY97, LYS100, GLY119, SER120, VAL143, ASN145 and 18 more
  • 5LGZ · Structure of Photoreduced Pentaerythritol Tetranitrate Reductase · FNR A403 · binds ALA23, PRO24, LEU25, THR26, ALA58, GLN100, HIS181, HIS184 and 9 more
  • 5LNJ · XenA - reduced - Y183F variant in complex with 7-hydroxycoumarin · FNR A401 · binds PRO22, PRO23, MET24, CYS25, GLU56, ALA57, GLN99, HIS178 and 9 more
  • 6M73 · Crystal structure of Enterococcus hirae L-lactate oxidase in complex with D-lactate form… · FNR A401 · binds TYR37, ILE38, ALA89, PRO90, VAL91, ALA92, SER119, GLN142 and 13 more
  • 6QLI · Crystal structure of F181Q UbiX in complex with FMN and dimethylallyl monophosphate · FNR A302 · binds THR12, GLY13, ALA14, SER15, SER39, ALA41, VAL45, SER104 and 4 more
  • 7JH4 · Crystal structure of NAD(P)H-flavin oxidoreductase (NfoR) from S. aureus complexed with… · FNR A301 · binds ARG15, HIS16, ALA17, LYS19, GLY71, GLN75, TYR145, LEU148 and 15 more
  • 7LJU · Porcine Dihydropyrimidine Dehydrogenase (DPD) crosslinked with 5-Ethynyluracil (5EU) · FNR A1108 · binds ALA549, SER550, ALA551, ALA552, LYS574, THR575, ILE590, ASN609 and 15 more
  • 8PRW · Cryo-EM structure of the yeast fatty acid synthase at 1.9 angstrom resolution · FNR G2302 · binds PRO595, GLY596, MET597, THR598, PRO599, CYS600, ASN650, ILE652 and 18 more
  • 8QH7 · Crystal structure of respiratory Complex I subunits NuoEF from Aquifex aeolicus bound to… · FNR B502 · binds GLY65, ARG66, GLY67, GLY68, PHE71, LYS76, ASN92, ASP94 and 13 more
  • 9FEA · Crystal Structure of reduced NuoEF variant P228R(NuoF) from Aquifex aeolicus bound to NAD+ · FNR B502 · binds GLY65, ARG66, GLY67, GLY68, ALA69, PHE71, LYS76, ASN92 and 14 more
  • 9FIH · Crystal Structure of NuoEF variant P228R(NuoF) from Aquifex aeolicus bound to NADH under… · FNR B502 · binds GLY65, ARG66, GLY67, GLY68, PHE71, LYS76, ASN92, ASP94 and 13 more
  • 5K9C · Crystal structure of human dihydroorotate dehydrogenase with ML390 · FNR A400 · binds ALA95, ALA96, GLY97, LYS100, GLY119, SER120, ASN145, TYR147 and 15 more
  • 5K9D · Crystal structure of human dihydroorotate dehydrogenase at 1.7 a resolution · FNR A400 · binds ALA95, ALA96, GLY97, LYS100, GLY119, SER120, ASN145, TYR147 and 15 more
  • 5LGZ · Structure of photoreduced pentaerythritol tetranitrate reductase · FNR A403 · binds ALA23, PRO24, LEU25, THR26, ALA58, GLN100, HIS181, HIS184 and 9 more
  • 5LNJ · Xena - reduced - Y183F variant in complex with 7-hydroxycoumarin · FNR A401 · binds PRO22, PRO23, MET24, CYS25, GLU56, ALA57, GLN99, HIS178 and 9 more
  • 5QIB · Pandda analysis group deposition of models with modelled events (E.G. bound ligands)… · FNR A401 · binds TYR26, TYR27, ALA79, THR80, ALA81, SER108, TRP110, GLN130 and 14 more
  • 6M73 · Crystal structure of enterococcus hirae L-lactate oxidase in complex with lactate · FNR A401 · binds TYR37, ILE38, ALA89, PRO90, VAL91, ALA92, SER119, GLN142 and 13 more
  • 6M74 · Crystal structure of enterococcus hirae L-lactate oxidase M207L in complex with lactate · FNR A401 · binds TYR37, ILE38, ALA89, PRO90, VAL91, ALA92, SER119, GLN142 and 13 more
  • 6QLH · Crystal structure of ubix in complex with reduced FMN and isopentyl monophosphate · FNR A303 · binds THR12, GLY13, ALA14, SER15, SER39, ALA41, LEU44, VAL45 and 5 more
  • 6QLI · Crystal structure of F181Q ubix in complex with FMN and dimethylallyl monophosphate · FNR A302 · binds THR12, GLY13, ALA14, SER15, SER39, ALA41, VAL45, SER104 and 4 more
  • 6QLL · Crystal structure of F181H ubix in complex with FMN and dimethylallyl monophosphate · FNR A402 · binds THR12, GLY13, ALA14, SER15, SER39, ALA41, VAL45, SER104 and 4 more
  • 7JH4 · Crystal structure of NAD(P)H-flavin oxidoreductase (nfor) from S. aureus complexed with… · FNR A301 · binds ARG15, HIS16, ALA17, LYS19, GLY71, GLN75, TYR145, PRO164 and 12 more

Residues it binds most

GLY 53, SER 49, THR 41, ALA 47, ASN 31, LYS 39, ARG 36, GLU 34, LEU 32, PRO 27 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • NA · Sodium ion
  • GOL · Glycerol
  • SF4 · Iron/sulfur cluster
  • CL · Chloride ion
  • 4LR · Dimethylallyl monophosphate
  • FAD · Flavin-adenine dinucleotide
  • FES · Fe2/s2 (inorganic) cluster
  • LAC · Lactic acid
  • NAD · Nicotinamide-adenine-dinucleotide
  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
  • ORO · Orotic acid

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