Research workbench
Crystal structure of THR316ALA mutant of jamm domain of S. pombe
Analyse Crystal structure of THR316ALA mutant of jamm domain of S. pombe in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7LM3
- Type
- protein
- Length
- 371 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Amsh-like protease SST2
- EC
- 3.4.19.-
- UniProt
- Q9P371
- Ligands
- ZN, PO4
- Pockets
- 4 · best druggability 0.50
Structure
x-ray diffraction · 2 distinct chains · 24% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Amsh-like protease SST2 (EC 3.4.19.-) | protein | 185 | 23% helix, 32% strand | Q9P371 |
| B | Amsh-like protease SST2 (EC 3.4.19.-) | protein | 186 | 24% helix, 32% strand | Q9P371 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 199 | 0.50 | 0.76 | 36 | empty |
| 2 | 140 | 0.44 | 0.76 | 26 | empty |
| 3 | 123 | 0.41 | 0.75 | 20 | empty |
| 4 | 71 | 0.30 | 0.74 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 232 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9P371
- Elsewhere: RCSB PDB 7LM3 · PDBe 7LM3 · UniProt Q9P371
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