GL1X · GenesisL1 explorer

MolNFT v1 · #438581 · protein

AlphaFold monomer V2.0 prediction for amsh-like protease SST2 (Q9P371)

Q9P371: “AlphaFold monomer V2.0 prediction for amsh-like protease SST2 (Q9P371)”. 4 pockets (best druggability 0.63). MolNFT v1 #438581 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9P371
Type
protein
Length
435 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x37980899ba05b13cE955B2984E29ee9e423A1753
Molecule
Amsh-like protease SST2
UniProt
Q9P371
Pockets
4 · best druggability 0.63

Structure

1 distinct chain · 36% helix, 15% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AAmsh-like protease SST2protein43536% helix, 15% strandQ9P371

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13870.630.7839empty
22500.600.7935empty
32830.540.7637empty
42020.460.7424empty

Compared structures

  • 4K1R · Crystal structure of Schizosaccharomyces pombe sst2 catalytic domain and Ubiquitin · an experimental structure of the same protein · chain A against A, TM-score 0.43
  • 4K1R · Crystal structure of schizosaccharomyces pombe SST2 catalytic domain and ubiquitin · an experimental structure of the same protein · chain A against A, TM-score 0.43
  • 4MS7 · Crystal structure of Schizosaccharomyces pombe sst2 catalytic domain · an experimental structure of the same protein · chain A against B, TM-score 0.43
  • 4MS7 · Crystal structure of schizosaccharomyces pombe SST2 catalytic domain · an experimental structure of the same protein · chain A against B, TM-score 0.43
  • 4JXE · Crystal structure of Schizosaccharomyces pombe sst2 catalytic domain · an experimental structure of the same protein · chain A against A, TM-score 0.43
  • 4JXE · Crystal structure of schizosaccharomyces pombe SST2 catalytic domain · an experimental structure of the same protein · chain A against A, TM-score 0.43
  • 4MSJ · Crystal structure of S. pombe amsh-like protease SST2 catalytic domain from P212121 space… · an experimental structure of the same protein · chain A against B, TM-score 0.43
  • 4MSJ · Crystal structure of S. pombe AMSH-like protease SST2 catalytic domain from P212121 space… · an experimental structure of the same protein · chain A against B, TM-score 0.43

Analyse

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