UniProt Q9P371
AMSH-like protease sst2 (Q9P371)
AMSH-like protease sst2 (UniProt Q9P371), EC 3.4.19.-: 26 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9P371
- Protein
- AMSH-like protease sst2
- EC
- 3.4.19.-
- Experimental structures
- 26
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 6 · 2 records with a druggable one
Structures
27 records of Q9P371 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4JXE | Crystal structure of Schizosaccharomyces pombe sst2 catalytic domain | x-ray diffraction | A, B | — | — |
| 4JXE | Crystal structure of schizosaccharomyces pombe SST2 catalytic domain | x-ray diffraction | A, B | — | — |
| 4K1R | Crystal structure of Schizosaccharomyces pombe sst2 catalytic domain and Ubiquitin | x-ray diffraction | A, C | — | — |
| 4K1R | Crystal structure of schizosaccharomyces pombe SST2 catalytic domain and ubiquitin | x-ray diffraction | A, C | — | — |
| 4MS7 | Crystal structure of Schizosaccharomyces pombe sst2 catalytic domain | x-ray diffraction | A, B | — | — |
| 4MS7 | Crystal structure of schizosaccharomyces pombe SST2 catalytic domain | x-ray diffraction | A, B | — | — |
| 4MSD | Crystal structure of Schizosaccharomyces pombe AMSH-like protein SST2 T319I mutant | x-ray diffraction | A, B | — | — |
| 4MSD | Crystal structure of schizosaccharomyces pombe amsh-like protein SST2 T319I mutant | x-ray diffraction | A, B | — | — |
| 4MSJ | Crystal structure of S. pombe AMSH-like protease SST2 catalytic domain from P212121 space group | x-ray diffraction | A, B, C | — | — |
| 4MSJ | Crystal structure of S. pombe amsh-like protease SST2 catalytic domain from P212121 space group | x-ray diffraction | A, B, C | — | — |
| 4MSM | Crystal structure of Schizosaccharomyces pombe AMSH-like protease sst2 E286A mutant bound to… | x-ray diffraction | A, C | — | — |
| 4MSM | Crystal structure of schizosaccharomyces pombe amsh-like protease SST2 E286A mutant bound to… | x-ray diffraction | A, C | — | — |
| 4MSQ | Crystal structure of Schizosaccharomyces pombe AMSH-like protease sst2 catalytic domain bound to… | x-ray diffraction | A, C | — | — |
| 4MSQ | Crystal structure of schizosaccharomyces pombe amsh-like protease SST2 catalytic domain bound to… | x-ray diffraction | A, C | — | — |
| 4NQL | The crystal structure of the DUB domain of AMSH orthologue, Sst2 from S. pombe, in complex with… | x-ray diffraction | A | — | — |
| 4NQL | The crystal structure of the dub domain of amsh orthologue, SST2 from S. pombe, in complex with… | x-ray diffraction | A | — | — |
| 4PQT | Insights into the mechanism of deubiquitination by JAMM deubiquitinases from co-crystal structures… | x-ray diffraction | A | — | — |
| 4PQT | Insights into the mechanism of deubiquitination by jamm deubiquitinases from co-crystal structures… | x-ray diffraction | A | — | — |
| 4ZD4 | Catalytic domain of Sst2 F403W mutant | x-ray diffraction | A, B | ZN | 2 (best 0.71) |
| 4ZD4 | Catalytic domain of SST2 F403W mutant | x-ray diffraction | A, B | — | — |
| 4ZD5 | Catalytic domain of Sst2 F403A mutant | x-ray diffraction | A, B | — | — |
| 4ZD5 | Catalytic domain of SST2 F403A mutant | x-ray diffraction | A, B | — | — |
| 4ZFR | Catalytic domain of SST2 F403A mutant bound to ubiquitin | x-ray diffraction | A | — | — |
| 4ZFT | Catalytic domain of Sst2 F403W mutant bound to ubiquitin | x-ray diffraction | A, C | ZN | — |
| 4ZFT | Catalytic domain of SST2 F403W mutant bound to ubiquitin | x-ray diffraction | A, C | — | — |
| 7LM3 | Crystal structure of THR316ALA mutant of jamm domain of S. pombe | x-ray diffraction | A, B | ZN, PO4 | — |
| Q9P371 | AlphaFold monomer V2.0 prediction for amsh-like protease SST2 (Q9P371) | predicted | A | — | 4 (best 0.63) |
Ligands
Experiment against prediction
- 4ZFT chain C against the predicted model Q9P371: TM-score 0.98, RMSD 0.66 Å
- 4ZFT chain C against the predicted model Q9P371: TM-score 0.98, RMSD 0.66 Å
- 4MSJ chain C against the predicted model Q9P371: TM-score 0.98, RMSD 0.70 Å
- 4MSJ chain C against the predicted model Q9P371: TM-score 0.98, RMSD 0.70 Å
- 4MSQ chain A against the predicted model Q9P371: TM-score 0.98, RMSD 0.86 Å
- 4MSQ chain A against the predicted model Q9P371: TM-score 0.98, RMSD 0.86 Å
- 4MS7 chain B against the predicted model Q9P371: TM-score 0.98, RMSD 0.73 Å
- 4MS7 chain B against the predicted model Q9P371: TM-score 0.98, RMSD 0.73 Å
- 4K1R chain A against the predicted model Q9P371: TM-score 0.98, RMSD 0.82 Å
- 4K1R chain A against the predicted model Q9P371: TM-score 0.98, RMSD 0.82 Å
Elsewhere
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