Research workbench
Structure of the human GLUN1-GLUN2B NMDA receptor in complex with S- KETAMINE,GLYCINE and glutamate
Analyse Structure of the human GLUN1-GLUN2B NMDA receptor in complex with S… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7EU8
- Type
- protein
- Length
- 3,010 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q05586, Q13224
- Ligands
- JC9, NAG
Structure
electron microscopy · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 761 | — | Q05586 |
| B | — | protein | 743 | — | Q13224 |
| C | — | protein | 772 | — | Q05586 |
| D | — | protein | 734 | — | Q13224 |
Ligands and binding sites
- JC9 · (2~{S})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one · ligand · chains A, B, C, D
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 7 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7EU8 · Structure of the human GluN1-GluN2B NMDA receptor in complex with S-ketamine,glycine and… · the same entry in another collection · chain A against A, TM-score 1.00
- Q05586 · AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, NMDA 1 (Q05586) · a predicted model of the same protein · chain A against A, TM-score 0.92
- Q13224 · AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, NMDA 2B (Q13224) · a predicted model of the same protein · chain B against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q05586
- Every structure of UniProt Q13224
- Elsewhere: RCSB PDB 7EU8 · PDBe 7EU8 · UniProt Q05586 · UniProt Q13224
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