UniProt Q13224
Glutamate receptor ionotropic, NMDA 2B (Q13224)
Glutamate receptor ionotropic, NMDA 2B (UniProt Q13224): 27 experimental structures on GenesisL1, 9 ligands bound, 89 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q13224
- Protein
- Glutamate receptor ionotropic, NMDA 2B
- Experimental structures
- 27
- Predicted models
- 0
- Ligands
- 9
- Pockets
- 89 · 12 records with a druggable one
Structures
27 records of Q13224 in the MolNFT archive: 27 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5EWJ | Crystal structure of amino terminal domains of the NMDA receptor subunit GLUN1 and GLUN2B in… | x-ray diffraction | B, D | NAG, QEL | — |
| 5EWJ | Crystal structure of amino terminal domains of the NMDA receptor subunit GLUN1 and GLUN2B in… | x-ray diffraction | B, D | — | — |
| 5EWL | Crystal structure of amino terminal domains of the NMDA receptor subunit GLUN1 and GLUN2B in… | x-ray diffraction | B, D | 5SL, NAG, NA | 14 (best 0.77) |
| 5EWL | Crystal structure of amino terminal domains of the NMDA receptor subunit GLUN1 and GLUN2B in… | x-ray diffraction | B, D | — | — |
| 5EWM | Crystal structure of amino terminal domains of the NMDA receptor subunit GLUN1 and GLUN2B in… | x-ray diffraction | B, D | NAG, 5SM, NA | 17 (best 0.77) |
| 5EWM | Crystal structure of amino terminal domains of the NMDA receptor subunit GLUN1 and GLUN2B in… | x-ray diffraction | B, D | — | — |
| 7EU8 | Structure of the human GluN1-GluN2B NMDA receptor in complex with S-ketamine,glycine and glutamate | electron microscopy | B, D | NAG, JC9 | 15 (best 0.86) |
| 7EU8 | Structure of the human GLUN1-GLUN2B NMDA receptor in complex with S- KETAMINE,GLYCINE and glutamate | electron microscopy | B, D | NAG, JC9 | — |
| 7KL0 | Cocrystal structure of human camkii-alpha (CAMK2A)KINASE domain and GLUN2B(S1303D) | x-ray diffraction | C, D | — | — |
| 7KL1 | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D) | x-ray diffraction | C, D | ATP | 4 (best 0.88) |
| 7KL1 | Cocrystal structure of human camkii-alpha (CAMK2A)KINASE domain and GLUN2B(S1303D) | x-ray diffraction | C, D | ATP | — |
| 7KL2 | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D) | x-ray diffraction | B | — | 2 (best 0.70) |
| 7KL2 | Cocrystal structure of human camkii-alpha (CAMK2A)KINASE domain and GLUN2B(S1303D) | x-ray diffraction | B | — | — |
| 7UIS | Cocrystal structure of human camkii-alpha (CAMK2A)KINASE domain and GLUN2B(S1303D) | x-ray diffraction | B | — | — |
| 7UJP | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B | x-ray diffraction | C, D | ADP, ATP, MG | 4 (best 0.83) |
| 7UJP | Cocrystal structure of human camkii-alpha (CAMK2A)KINASE domain and GLUN2B | x-ray diffraction | C, D | ADP, ATP, MG | — |
| 7UJQ | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B | x-ray diffraction | C, D | — | 5 (best 0.88) |
| 7UJQ | Cocrystal structure of human camkii-alpha (CAMK2A)KINASE domain and GLUN2B | x-ray diffraction | C, D | — | — |
| 7UJR | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B | x-ray diffraction | B | — | 1 (best 0.68) |
| 7UJR | Cocrystal structure of human camkii-alpha (CAMK2A)KINASE domain and GLUN2B | x-ray diffraction | B | — | — |
| 7UJS | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B in complex with ADP | x-ray diffraction | B | — | 1 (best 0.70) |
| 7UJS | Cocrystal structure of human camkii-alpha (CAMK2A)KINASE domain and GLUN2B in complex with ADP | x-ray diffraction | B | — | — |
| 7UJT | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D) in complex with… | x-ray diffraction | B | — | 2 (best 0.66) |
| 7UJT | Cocrystal structure of human camkii-alpha (CAMK2A)KINASE domain and GLUN2B(S1303D) in complex with… | x-ray diffraction | B | — | — |
| 8VUU | Human GluN1-2B with Fab 007-168 | electron microscopy | B, D | — | 17 (best 0.84) |
| 8VUV | Human GluN1-2B with Fab 007-168 Local refinement of ATD | electron microscopy | B | — | 7 (best 0.80) |
| Q13224 | AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, NMDA 2B (Q13224) | — | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 5 records
- ATP · Adenosine-5'-triphosphate · in 4 records
- ADP · Adenosine-5'-diphosphate · in 2 records
- JC9 · (2~{S})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one · in 2 records
- MG · Magnesium ion · in 2 records
- NA · Sodium ion · in 2 records
- 5SL · ~{N}-[(1~{S},3~{S})-3-[3-[(4-methylphenyl)methyl]-1,2,4-oxadiazol-5-yl]cyclopentyl]-1~{H}-pyrazolo[3,4-d]pyrimidin-4-amine · in 1 record
- 5SM · 5-[3-[bis(fluoranyl)methyl]-4-fluoranyl-phenyl]-3-[(2-methylimidazol-1-yl)methyl]pyridazine · in 1 record
- QEL · 4-[(1R,2S)-2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol · in 1 record
Elsewhere
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