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The crystal structure of sorting nexin 27 and pbm complex

Analyse The crystal structure of sorting nexin 27 and pbm complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7E0B
Type: protein
Length: 103 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sorting nexin-27; Pbm
UniProt: Q96L92
Pockets: 1 · best druggability 0.33

Structure

x-ray diffraction · 2 distinct chains · 14% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sorting nexin-27	protein	96	15% helix, 41% strand	Q96L92
B	Pbm	protein	7	0% helix, 71% strand	—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	62	0.33	0.76	16	empty

Interfaces

1 interface between chains.

A–B · 546 Å² buried · 17 hydrogen bonds · protein-protein

Compared structures

7E0B · The crystal structure of sorting nexin 27 and PBM complex · the same entry in another collection · chain A against A, TM-score 1.00
Q96L92 · AlphaFold monomer V2.0 prediction for sorting nexin-27 (Q96L92) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96L92
Elsewhere: RCSB PDB 7E0B · PDBe 7E0B · UniProt Q96L92

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